Diagnostic gastrointestinal procedures like endoscopy and colonoscopy have revolutionized the detection and management of digestive disorders. While upper endoscopy allows specialists to examine the esophagus, stomach, and the initial segment of the small intestine, colonoscopy provides a detailed view of the large bowel and the lower digestive tract.

In the past, many individuals overlooked warning signs like persistent gastric discomfort, unexplained abdominal pain, or rectal bleeding, often relying on self-medication. Today, early endoscopic evaluation enables the detection of microscopic tissue changes and abnormal growths—most notably gastrointestinal polyps—long before they progress into malignant conditions.

What Are Gastrointestinal Polyps?

Polyps are abnormal tissue growths that develop along the inner lining of the digestive tract, including the stomach, small intestine, and colon. While many polyps are benign in their early stages, certain varieties have the potential to become cancerous if left untreated over time.

Polyps generally present in two structural forms:

  • Pedunculated Polyps: These growths are attached to the intestinal wall by a narrow, stalk-like stem (resembling a small mushroom). Because they protrude from the wall, they can easily be removed during a standard endoscopy or colonoscopy using a specialized wire snare loop (polypectomy).

  • Sessile or Flat Polyps: These polyps lie flat and spread horizontally along the intestinal wall. They can range from small lesions to large growths spanning 5 to 8 centimeters or more. Because they lack a stalk and adhere closely to the mucosal layers, standard snare polypectomy is often insufficient or unsafe for removing them completely.

The Shift from Open Surgery to Advanced Endoscopy

Historically, removing large, flat, or suspicious polyps required major invasive abdominal surgery. Surgeons had to resect (cut away) entire segments of the stomach or colon and rejoin the remaining bowel ends, requiring extensive hospital stays and prolonged recovery times.

Advances in therapeutic endoscopy have transformed this approach. By utilizing high-resolution imaging, targeted biopsies, and imaging scans (such as CT or MRI when needed), specialists can precisely assess:

  • The exact depth of tissue invasion within the intestinal wall layers.

  • Whether the lesion is non-cancerous, pre-cancerous, or an early-stage malignancy suitable for local removal.

What Is Endoscopic Submucosal Dissection (ESD)?

Endoscopic Submucosal Dissection (ESD) is an advanced, minimally invasive endoscopic technique developed and perfected to remove large, flat polyps and early gastrointestinal tumors in a single, intact piece (en bloc resection).

How ESD Works:

  1. Precise Endoscopic Access: An endoscope equipped with specialized micro-instruments is guided directly to the site of the polyp.

  2. Submucosal Injection: A specialized fluid is injected underneath the lesion into the submucosal layer, lifting the abnormal growth away from the deeper muscular wall of the bowel to create a protective cushion.

  3. Targeted Micro-Dissection: Using electrosurgical micro-knives, the specialist carefully dissects and separates the flat polyp from the surrounding deeper tissue, removing it completely without cutting open the abdomen.

Key Advantages of the ESD Technique

  • Organ Preservation: Avoids major surgery and preserves the natural anatomy and function of the stomach and colon.

  • Scar-Free and Minimally Invasive: The entire procedure is performed internally through natural digestive pathways, resulting in no external surgical cuts or scars.

  • Complete Lesion Removal: Enables full removal of flat lesions larger than several centimeters in one piece, allowing accurate microscopic evaluation of the tissue margins to confirm complete cure.

  • Faster Recovery: Patients experience significantly less post-procedure pain, reduced risk of complications, and a much shorter hospital stay compared to conventional surgical resections.

Summary

Gastrointestinal polyps and early mucosal growths no longer require major open or laparoscopic bowel resections. Through modern diagnostic endoscopies and advanced techniques like Endoscopic Submucosal Dissection (ESD), flat and large growths can be completely and safely removed from within the digestive tract, ensuring effective cancer prevention and a rapid return to normal life.

Dr. KM Cherian Institute of Medical Sciences is a pioneer in delivering world-renowned treatment procedures at affordable costs. We continually upgrade the quality of the healthcare ecosystem and enable faster recovery for patients from all backgrounds.