Minimally Invasive Hybrid Surgery for Ileal Interposition (MIHSII) for the Resolution of Type 2 Diabetes
Sleeve gastrectomy leads to caloric restriction and a reduction of fat mass. The procedure causes a reduction in the circulating levels of adipokines, which reverses insulin resistance. Bariatric surgery of any form, thus, has a short- and long-term impact on blood glucose levels. The short-term impact is because of the decreased stimulation of the entero-insular axis secondary to decreased calorie intake, and the long-term effect is mediated by reduced fat mass. Bariatric surgery leads to the resolution of T2DM within a week, prior to the significant weight loss that occurs over several months. This finding demonstrates that weight-independent factors are…